Table 1

Mean lattice index values for the association and pyramidal WMT fibres in controls and probable Alzheimer's disease cohorts

Controls Grouped AD Mild AD1-151
Splenium of corpus callosum0.65 (0.01) l-r0.56 (0.02)1-165 0.60 (0.02)1-150
0.65 (0.06) a-p0.43 (0.05)1-165 0.46 (0.03)1-150
Superior longitudinal fasciculus0.46 (0.02) a-p0.39 (0.01)1-168 0.40 (0.01)1-168
Cingulum
 Left0.37 (0.01) a-p0.33 (0.01)1-150 0.35 (0.02)
 Right0.35 (0.01) a-p0.33 (0.01)0.35 (0.02)
Internal capsule—posterior limb
 Left arm0.39 (0.01) v0.39 (0.01)0.40 (0.01)
 Right arm0.38 (0.01) v0.38 (0.01)0.38 (0.01)
  • 1-150 p<0.05,

  • 1-160 p<0.01,

  • 1-165 p<0.005,

  • 1-168 p<0.0001.

  • Measures of anisotropy are given as the lattice index (SEM).

  • 1-151 (MMSE >17); a-p=anterior-posterior; l-r=left-right; v=vertically oriented fibres.