Table 2

Clinical profiles of patients with anti-GQ1b IgG antibody

	Total	Acute ophthalmoparesis	MFS	MFS/GBS	GBS	BBE/GBS	BBE	Unclassified
Patients (n)	194	15	110	31	8	11	12	7
Sex (men/women)	106/88	6/9	66/44	16/15	4/4	5/6	5/7	4/3
Median age (range)	37 (2–78)	30 (9–69)	41 (2–78)	33 (6–76)	36 (17–50)	42 (24–76)	37 (27–69)	31 (18–66)
Antecedent illness:	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)
Upper respiratory infection	80	60	86	74	63	82	75	71
Diarrhoea	14	27	10	19	63	0	0	14
Initial symptoms:
Diplopia	67	100	75	39	0	55	75	71
Gait disturbance	29	0	32	42	75	18	33	43
Limb weakness	12	0	3	35	100	9	0	14
Photophobia	8	0	10	10	0	0	0	14
Dysarthria	7	7	4	16	0	18	8	14
Dysphagia	2	0	2	3	0	0	0	0
Dysaesthesia	4	0	3	10	13	9	0	0
Blepharoptosis	2	0	3	0	0	0	8	0
Consciousness disturbance	1	0	0	0	0	9	8	0
Neurological signs during the course of the illness:
Consciousness disturbance
Drowsiness	7	0	3	13	0	36	17	0
Stupor, semicoma, coma	4	0	0	0	0	27	33	0
Blepharoptosis	45	40	51	42	0	36	17	29
External ophthalmoplegia	91	100	100	100	0	100	100	100
Internal ophthalmoplegia	36	7	37	52	0	27	42	29
Nystagmus	22	27	16	29	25	18	33	57
Facial weakness	34	13	23	71	13	82	33	14
Bulbar palsy	29	13	20	61	13	82	25	14
Limb weakness^2-150	26	0	0	100	100	100	0	14
Tendon reflex
Brisk	4	0	0	0	0	9	33	0
Normal	6	47	0	0	0	0	0	100
Decreased	30	33	29	32	62	35	25	0
Absent	60	20	71	68	38	56	42	0
Babinski's sign	8	0	0	0	0	64	67	0
Ataxia	80	0	100	68	0	45	100	100
Deep sense impairment	26	0	27	39	13	55	8	29
Superficial sense impairment	35	20	36	42	38	36	8	29
CSF albuminocytological dissociation	58	25	66	43	25	75	42	80

MFS= Miller Fisher syndrome; GBS=Guillain-Barré syndrome; BBE=Bickerstaff's brain stem encephalitis; MFS/GBS=overlapping Miller Fisher syndrome and Guillain-Barré syndrome; BBE/GBS=overlapping Bickerstaff's brain stem encephalitis and Guillain-Barré syndrome.
↵2-150 3 or less on the Medical Research Council scale