Symptomatic measurements
| Variable | CFS patients n=66 | Depressed patients n=15 | Sedentary controls n=30 | ANOVA p Value |
| HAD anxiety score | 5 (2–8) | 10 (7–13) | 7 (4–10) | 0.0005 |
| HAD depression score | 5 (2.5–7.5) | 11 (9–13) | 5.5 (1.5–9.5) | <0.0001 |
| Somatic amplification score | 10 (7–13) | 7 (4.5–9.5) | 5.5 (2–9) | 0.03 |
| PSQI sleep score | 6 (4.5–7.5) | 9 (5–13) | 5 (2–8) | 0.08 |
| Total fatigue | 318 (47) | 296 (67) | 213 (52) | <0.0001 |
| Mental fatigue | 155 (132–178) | 150 (120–181) | 106 (89–123) | <0.0001 |
| Physical fatigue | 175 (159–192) | 138 (107–169) | 101 (90–122) | <0.0001 |
| Chalder fatigue | 30 (25.5–34.5) | 27 (20–34) | 14 (9.5–18.5) | <0.0001 |
| SF-36 physical function | 45 (35–55) | 85 (70–100) | 93 (73–100) | <0.0001 |
| SF-36 role physical | 0 (0–25) | 50 (0–100) | 100 (75–100) | <0.0001 |
| SF-36 bodily pain | 62 (41–83) | 44 (31–52) | 84 (74–94) | <0.0001 |
| SF-36 general health | 37 (25–50) | 45 (23–68) | 67 (55–79) | <0.0001 |
| SF-36 vitality | 25 (15–35) | 20 (5–35) | 60 (46–64) | <0.0001 |
| SF-36 social function | 38 (13–63) | 50 (31–69) | 100 (84–100) | <0.0001 |
| SF-36 role emotional | 67 (34–100) | 0 (0–33) | 100 (83–100) | <0.0001 |
| SF-36 mental health | 64 (53–75) | 36 (22–50) | 74 (61–88) | <0.0001 |
Values are mean (SD) or median (interquartile range).
Normal or usual scores are 14 for Chalder questionnaire, 200 for total fatigue, and 100 for physical and mental fatigue scores (visual analogue scales). 100 is the maximum (full capacity) SF-36 score for subscales. A score< 8 on hospital anxiety and depression (HAD) scale is considered non-pathological. A Pittsburgh sleep quality index (PSQI) score<6 is considered non-pathological.