Magnetisation transfer ratio histogram derived metrics of the brain and cervical cord from the whole patient sample and the three multiple sclerosis (MS) phenotypes
All patients | RRMS | SPMS | PPMS | p Value | |
Average MTR: brain (%) | 39.2 (1.3) | 39.4 (1.6) | 38.7 (1.0) | 39.7 (0.6) | NS |
Peak height: brain | 103.8 (14.9) | 106.0 (16.2) | 100.0 (14.1) | 105.9 (8.4) | NS |
Peak location: brain (%) | 34.4 (1.7) | 34.6 (1.6) | 33.6 (1.7) | 35.4 (1.0) | 0.007 |
Average MTR: cord (%) | 44.4 (2.4) | 44.9 (2.3) | 43.8 (2.5) | 43.7 (1.5) | NS |
Peak height: cord | 63.9 (15.2) | 66.5 (17.5) | 60.9 (11.1) | 61.8 (15.1) | NS |
Peak location: cord (%) | 39.1 (3.4) | 40.2 (3.1) | 38.1 (3.3) | 37.3 (4.0) | 0.01 |
Values are expressed as means (SD). MTR=Magnetisation transfer ratio; RRMS=relapsing-remitting MS; SPMS=secondary progressive MS; PPMS=primary progressive MS. For statistical analysis, see text.