Early MR findings in 68 patients with clinically isolated syndromes of whom 18 developed multiple sclerosis (MS)1-150 within 1 year
| MRI index |
Cut off point |
Prevalence n (%) |
MS n |
PPV % |
Sensitivity % |
Specificity % |
| Baseline MRI: | ||||||
| Lesions on T2 weighted imaging | 1 | 48 (71) | 16 | 33 | 89 | 36 |
| 4 | 37 (54) | 14 | 38 | 78 | 54 | |
| 9 | 25 (37) | 11 | 44 | 61 | 72 | |
| Contrast enhancing lesions | 1 | 21 (31) | 11 | 52 | 61 | 80 |
| Baseline and follow up MRI: | ||||||
| Lesions on T2 weighted imaging at baseline and new lesions at follow up | 1 | 27 (40) | 15 | 55 | 83 | 76 |
| Contrast enhancing lesions at baseline and new contrast enhancing lesions at follow up | 1 | 10 (15) | 7 | 70 | 39 | 94 |
↵1-150 Clinically probable or definite MS.