Table 2

Mean (SD) neuropsychological test results for the patient groups and controls

Test (maximum score) AD DLB Controls One way Anova F value p Value Significant group effects
Memory:
 Digit span
  Forwards6.3  (1.1)5.2  (1.3)7.0  (1.0)7.10.0031 2-151
  Backwards3.7 (0.9)2.3 (1.0)5.2 (1.5)16.90.0000 2-150 2-151 2-152
 Logical memory
  Immediate (24)2.4 (1.4)4.8 (3.0)8.8 (1.9)28.90.0000 2-150 2-151 2-152
  Delayed (24)0.1 (0.3)1.8 (2.6)7.0 (2.2)40.30.0000 2-151 2-152
  % Recall after delay3.7 (11.1)27.9 (35.6)78.2 (15.0)39.80.0000 2-150 2-151 2-152
 RMT
  Words (25)16.9 (3.3)15.1 (4.1)24.6 (1.0)42.40.0000 2-151 2-152
  Faces (25)18.4 (3.8)16.9 (4.3)24.5 (0.6)24.90.0000 2-151 2-152
 Category fluency: total correct23.6 (5.6)23.4 (11.9)53.8 (9.5)42.90.0000 2-151 2-152
 Graded naming test (30)14.6 (8.1)13.1 (4.5)25.4 (2.1)200.0000 2-151 2-152
Perceptual tasks:
 VOSP
  Screening (20)19.3 (1.1)18.7 (1.4)19.5 (0.7)2.10.1415
  Fragmented letters (20)18.3 (1.1)8.9 (5.4)19.2 (0.9)42.10.0000 2-150 2-151
  Silhouette identification (30)15.4 (5.6)15.8 (4.2)21.8 (2.9)10.30.0004 2-151 2-152
  Object decision (20)16.3 (3.5)11.8 (4.6)17.1 (2.4)7.50.0023 2-150 2-151
  Cube analysis (10)7.9 (2.5)3.4 (2.6)9.6 (1.0)30.60.0000 2-150 2-151
Attentional tasks:
 TEA
  Elevator counting (7)5.6 (1.4)3.9 (2.6)6.8 (0.4)8.50.0012 2-151
  Elevator counting +distraction (10)4.1 (2.4)2.6 (3.3)8.5 (1.9)17.40.0000 2-151 2-152
  Map search total score (80)30.3 (14.5)11.8 (11.7)61.3 (11.4)44.80.0000 2-150 2-151 2-152
 Stroop: colour/word condition, No read (112)30.4 (17.2)NA102.1 (16.7)104.20.0000 2-152
 Della Sala
  Task 1: proportion of correct spans0.6 (0.2)0.7 (0.2)0.5 (0.3)0.80.4514
  Task 2: No crosses (ca 180)108.6 (25.8)60.5 (46.3)147.5 (27.0)16.10.0000 2-150 2-151 2-152
  Task 3: No crosses (ca 180)70.1 (21.9)28.7 (25.6)109.0 (39.9)13.20.0001 2-150 2-151 2-152
  Task 3: proportion of correct spans0.7 (0.2)0.6 (0.2)0.6 (0.3)0.20.7884
  Combined decrement score1.6 (3.6)7.1 (5.7)1.6 (4.1)3.80.0362 2-150 2-151
 WCST
  No categories correct (6)3.4 (1.9)NA5.9 (0.4)11.70.0003 2-152
  No perseverative errors7.0 (5.4)NA1.4 (2.8)5.70.0102 2-152
 FAS Verbal fluency: total correct21.5 (9.3)17.8 (17.9)39.1 (11.1)4.60.0219 2-151
  • AD=Alzheimer's disease; LDB=Lewy bodies with dementia.

  • 2-150 Significant group effect between AD and DLB patients.

  • 2-151 Significant group effect between DLB patients and controls.

  • 2-152 Significant group effect between AD patients and controls.

  • NA=Not appropriate (see text).