Performance of consensus clinical diagnostic criteria for DLB and of anosmia
Consensus DLB criteria2-150 | Anosmia | |
All cases (n=92): | ||
Sensitivity | colo64 | 53 |
Specificity | 89 | 84 |
PPV | 58 | 43 |
Definite AD(n=54)2-151 | ||
Sensitivity | 33 | 55 |
Specificity | 88 | 82 |
PPV | 38 | 38 |
Not definite AD (n=38) | ||
Sensitivity | 100 | 50 |
Specificity | 90 | 87 |
PPV | 73 | 50 |
AD=Alzheimer's disease; DLB=dementia with Lewy bodies; PPV=positive predictive value (%); neuropathological criterion for DLB=LBs present in both SN and cingulate gyrus.
↵2-150 At least two of visual hallucinations for at least 4 months, persistent brief fluctuations (item 272 of CAMDEX), and at least one feature of parkinsonism.
↵2-151 CERAD criteria for definite AD.