Mean (SD) MTR and D̄ histogram derived metrics of NAWM and NAGM from controls and patients with multiple sclerosis
CTRLs | MS | p Values1-150 | |
No of subjects | 18 | 30 | — |
NAWM: | |||
Mean MTR (%) | 41.2 (0.8) | 38.9 (1.3) | 0.001 |
MTR peak location (%) | 35.2 (1.0) | 33.8 (1.8) | 0.004 |
MTR peak height | 169.3 (20.7) | 147.5 (23.4) | 0.002 |
MeanD̄(mm2/s×10−3) | 0.820 (0.036) | 0.843 (0.038) | 0.04 |
D̄ Peak location | 0.745 (0.033) | 0.764 (0.032) | NS |
D̄ Peak height | 134.1 (15.3) | 119.3 (18.8) | 0.007 |
NAGM: | |||
Mean MTR (%) | 39.7 (0.5) | 39.2 (0.6) | 0.005 |
MTR Peak location | 32.8 (1.0) | 31.4 (1.6) | 0.001 |
MTR Peak height | 130.9 (11.9) | 132.7 (12.4) | NS |
MeanD̄(mm2/s×10−3) | 1.052 (0.050) | 1.086 (0.570) | 0.04 |
D̄ Peak location | 0.848 (0.034) | 0.857 (0.035) | NS |
D̄ Peak height | 68.2 (9.2) | 61.3 (8.5) | 0.01 |
↵1-150 Student's t test for non-paired data.
MTR=Magnetisation transfer ratio; D̄=diffusivity.