Baseline T2 and T1 lesion loads and brain parenchymal (BP) volumes and changes over 2 years in patients with relapsing-remitting multiple sclerosis
|
Baseline (53 patients) |
Follow up (53 patients) | p Value | |
| T2 lesion load (ml): | 0.005 | ||
| Mean (SD) | 5.7 (5.9) | 7.4 (7) | |
| Range | 0.02–29.9 | 0.23–27 | |
| T2 change over 2 y: | |||
| Mean (%) | +1.7 (29.8) | ||
| (95% CI) | (1.3–2.2) | ||
| T1 lesion load (ml) | 0.004 | ||
| Mean (SD) | 0.8 (1.1) | 1 (1.1) | |
| Range | 0–5.3 | 0–5.3 | |
| T1 change over 2 y: | |||
| Mean (%) | +0.2 (25) | ||
| (95% CI) | (0.15–0.26) | ||
| BP volume (ml) | <0.0001 | ||
| Mean (SD) | 1219.1 (76.8) | 1186.8 (80.7) | |
| Range | 1054.1–1306.3 | 981.9–1289.2 | |
| BP change over 2 y: | |||
| Mean (%) | −32.3 (2.65) | ||
| (95% CI) | (24.2–42.3) | ||
Comparison between the baseline and the follow up was performed by paired t test.