Table 2

Perturbations which could lead to raised ICP

 Increased cerebral volume-increased ISF volume
-increased blood volume
-increased tissue volume
Increased CSF production rate
Increased CSF outflow resistance
 Increased cerebral arterial pressure transmitted to capillaries (loss of autoregulation)
Increased cerebral venous pressure-leading to increased venous blood volume and increased ISF volume
-leading to reduced CSF outflow
  • ISF=Interstitial fluid.