Table 2

Correlations between NPI neuropsychiatric symptoms and motor and cognitive measures for patients with HD

NPI ScaleChoreaMMSE2-151DRS2-152DRS Subscales
AttentionConceptualisationConstructionInitiation and perseverationMemory
Agitation−0.02−0.09−0.11−0.15−0.130.02−0.10−0.01
Dysphoria−0.180.110.300.412-160 0.25−0.210.29−0.05
Irritability−0.14−0.09−0.08−0.23−0.18−0.080.01−0.00
Anxiety0.110.060.090.130.11−0.010.06−0.03
Apathy−0.12−0.15−0.070.01−0.12−0.160.04−0.17
Euphoria0.17−0.080.06−0.07−0.070.090.090.10
Disinhibition0.050.01−0.10−0.24−0.23−0.090.040.04
Delusions−0.230.240.220.06−0.070.090.362-160 0.22
Aberrant motor0.120.090.240.372-160 0.372-160 −0.150.18−0.01
Hallucinations−0.120.210.150.150.090.110.20−0.12
NPI Total−0.030.010.040.03−0.03−0.120.11−0.02
  • NPI=Neuropsychiatric inventory; DRS=Mattis dementia rating scale; MMSE=mini mental state examination; HD=Huntington's disease.

  • 2-151 n=50;

  • 2-152 n=52.

  • 2-160 p <0.01.