Comparison of patients with pituitary apoplexy with and without identified associated conditions
| Associated condition n=9 (30%) | No associated condition n=21 (70%) | p Value | |
| Sex | 4 women/5 men | 10 women/11 men | NS |
| Mean age (range) | 59 y (21–82) | 48 y (22–90) | NS |
| Known pituitary adenoma | 1 (11%) | 5 (23.8%) | NS |
| Neuro-ophthalmic deficit: | 8 (88.8%) | 17 (81.1%) | NS |
| Headache | 9 (100%) | 21 (100%) | NS |
| Ophthalmoplegia | 6 (66.6%) | 11 (52.4%) | NS |
| Optic nerve compression | 4 (44%) | 7 (33%) | NS |
| Chiasmal visual field defect | 4 (44%) | 10 (47.6%) | NS |
| Altered mental status | 5 (55%) | 4 (19%) | <0.05 |
| Systemic hypertension | 5 (55%) | 8 (38%) | NS |
| Neuroimaging: | |||
| Haemorrhage | 6 (66.6%) | 9 (42.8%) | NS |
| Infarction | 3 (33.3%) | 12 (57.1%) | NS |
| Prognosis: | |||
| Death | 0 | 0 | NS |
| Unknown | 2 (22.2%) | 7 (33.3%) | NS |
| Pituitary dysfunction | 5/9 (55.5%) | 11/21 (52.4%) | NS |
| Complete recovery | 2/7 (28.5%) | 10/14 (71%) | 0.06 |
| Neurological sequelae | 1/7 (14.3%) | 0 (0%) | NS |
| Neuro-ophthalmic sequelae | 5/7 (71.4%) | 2/14 (14.3%) | <0.01 |
| Ophthalmoplegia | 1/6 (16.6%) | 2/11 (18.2%) | NS |
| Severe optic neuropathy | 3/4 (75%) | 1/7 (14.3%) | <0.05 |
| Visual field defect | 4/4 (100%) | 2/10 (20%) | <0.01 |
| Mean delay in diagnosis (range) | 5.5 days (1–14) | 5.6 days (1–14) | NS |
| Mean delay in treatment (range) | 2.2 days [0–7] | 2.2 days (0–)] | NS |
p Calculated using χ2 and Student'st tests.