Clinimetric characteristics of HQoL scales
| Reliability | Validity | |||||
|---|---|---|---|---|---|---|
| Scale | Intern consist | Test-retest | Content | Construct | Factorial | Responsiveness |
| n, Number of patients; α, Cronbach's α; r, Pearson; r3, Spearman; ICC, intraclass correlation coefficient; +++, good; ++ , adequate; fair; −, poor; 0, no numerical results reported; ?, unclear; SES, Schwab and England scale; Beck's DI, Beck's depression inventory; S, significant; NS, not significant; SRM, standardised response mean. | ||||||
| PDQ-39 | α Total scale: | r=0.68–0.949 | +++9 | Generic HRQoL scales: | Eight factors9 | SRM for mobility and ADL: |
| 0.84–0.94142327 | (n=167; 3–6 days) | Range subscales PDQ-39 and SF-36: r=−0.34–−0.809 | Mobility | 0.55 and 0.43, respectively | ||
| Summary indices of PDQ-39 and EQ-5D: rs=−0.7528 | ADL | (n=51, 4 month interval)24 | ||||
| α Subscales: | Disease specific scales: | Emotional | Change PDQ-39 compared | |||
| 0.69–0.949 or | H and Y: rs=0.602829 | Stigma | with change in24: | |||
| 0.66–0.9527 or | H and Y v PDQ subscales, range: rs=0.16–0.72 2427 | Social support | Columbia: NS | |||
| 0.57–0.9423 | SES: rs=−0.662829 | Cognition | H and Y: NS | |||
| UPDRS-ME: rs=0.4129 | Communication | SF-36: S | ||||
| Item-total correlation: | Columbia, range subscales: rs=0.08–0.582427 | Bodily discomfort | Self report change: S | |||
| 0.67–0.919 | Other measures: | |||||
| Beck's DI with PDQ 39 SI: rs=0.6828and with PDQ 39 emotional: r=0.7325 | Four subscales (mobility, ADL, stigma, social support) show significant deterioration PDQ-39 more responsive than GHQ-28 and OPCS25 | |||||
| Barthel index with PDQ 39 ADL: rs=0.325 | PDQ-39 more responsive than GHQ-28 and OPCS25 | |||||
| MMSE: rs=−0.322829 | ||||||
| Analysis of group differences: | ||||||
| • by self reported severity: S9 | ||||||
| By H and Y (clinic sample) : S (except social)27 or S (except emotional, stigma, social, cognitions, bodily discomfort)23 | ||||||
| By H and Y (population sample): s30 (except social and stigma) | ||||||
| PDQL | α Total scale: | 0 | ++10 | Generic HRQoL scales: | Four factors10: | 0 |
| 0.9410–0.9521 | SF24 Mental health v PDQL emotional: r=0.6610 | Parkinsonian | ||||
| SF24, related domains: range r=0.46–0.6410 | Systemic | |||||
| α Subscales: | Disease specific measures: | Social | ||||
| 0.80–0.8710 or | “Webster contributes significant to QoL”21 | Emotional | ||||
| 0.77–0.8721 | Other measures: | |||||
| CES D v PDQL emotional: r=−0.7910 | ||||||
| MOS soc support survey v PDQL-social: r=0.1310 | ||||||
| “CAMCOG/GDS 15 contribute significant to QoL”21 | ||||||
| Analysis of group differences: | ||||||
| By SES, 3 levels: S10 | ||||||
| By Webster, 3 levels: S (all, except emotional)21 | ||||||
| PLQ | α Total scale: 0.9512 | Total scale: | ++12 | Generic HRQoL scales: | 9 Subscales, 1 or 2 factors/subscale, >50% variance12 | 2 Week interval |
| r=0.8712 | EORTC QLQ30: r=0.67 (n=111)12 | No external criterion | ||||
| α Subscales: 0.62–0.8712 | Disease specific measures: | Depression | (n=16)12 | |||
| Subscales: | H and Y: r=0.27, NS (n=21–29)12 | Physical achievement | ||||
| Correlation subscale–total scale: | r=0.69–0.8612 | SES: r=−0.27, NS (n=21–29)12 | Leisure | |||
| r=0.73–0.8612 | (n=65; 14 days) | Other measures: | Concentration | |||
| (n=405) | QoL VAS: r=−0.28, NS (n=21–29)12 | Social integration | ||||
| ADL scale: r=0.73 (n=111)12 | Insecurity | |||||
| Restlessness | ||||||
| Activity limitation | ||||||
| Anxiety | ||||||
| PIMS | α Total scale: 0.9011 | ICC=0.7211 | −11 | Analysis of group differences: | 4 Factors, 72% variance11: | 0 |
| (n=149; 1 month) | (Consensus) | By self assessed fluctuations: S (only between stable patients and fluctuating patients at their worst)11 | Psychological | |||
| Correlation among factors: | Social | |||||
| r=0.10–0.4611 | Physical | |||||
| Financial | ||||||