Table 3

Clinimetric characteristics of HQoL scales

ScaleIntern consistTest-retestContentConstructFactorialResponsiveness
n, Number of patients; α, Cronbach's α; r, Pearson; r3, Spearman; ICC, intraclass correlation coefficient; +++, good; ++ , adequate; fair; −, poor; 0, no numerical results reported; ?, unclear; SES, Schwab and England scale; Beck's DI, Beck's depression inventory; S, significant; NS, not significant; SRM, standardised response mean.
PDQ-39α Total scale:r=0.68–0.949+++9 Generic HRQoL scales: Eight factors9SRM for mobility and ADL:
    0.84–0.94142327(n=167; 3–6 days)Range subscales PDQ-39 and SF-36: r=−0.34–−0.809Mobility0.55 and 0.43, respectively
Summary indices of PDQ-39 and EQ-5D: rs=−0.7528ADL(n=51, 4 month interval)24
α Subscales: Disease specific scales: EmotionalChange PDQ-39 compared
    0.69–0.949 orH and Y: rs=0.602829Stigmawith change in24:
    0.66–0.9527 orH and Y v PDQ subscales, range: rs=0.16–0.72 2427Social supportColumbia: NS
    0.57–0.9423SES: rs=−0.662829CognitionH and Y: NS
UPDRS-ME: rs=0.4129CommunicationSF-36: S
Item-total correlation:Columbia, range subscales: rs=0.08–0.582427Bodily discomfortSelf report change: S
    0.67–0.919 Other measures:
Beck's DI with PDQ 39 SI: rs=0.6828and with PDQ 39 emotional: r=0.7325Four subscales (mobility, ADL, stigma, social support) show significant deterioration PDQ-39 more responsive than GHQ-28 and OPCS25
Barthel index with PDQ 39 ADL: rs=0.325PDQ-39 more responsive than GHQ-28 and OPCS25
MMSE: rs=−0.322829
Analysis of group differences:
• by self reported severity: S9
By H and Y (clinic sample) : S (except social)27 or S (except emotional, stigma, social, cognitions, bodily discomfort)23
By H and Y (population sample): s30 (except social and stigma)
PDQLα Total scale:0++10 Generic HRQoL scales: Four factors10:0
    0.9410–0.9521SF24 Mental health v PDQL emotional: r=0.6610Parkinsonian
SF24, related domains: range r=0.46–0.6410Systemic
α Subscales: Disease specific measures: Social
    0.80–0.8710 or“Webster contributes significant to QoL”21Emotional
    0.77–0.8721 Other measures:
CES D v PDQL emotional: r=−0.7910
MOS soc support survey v PDQL-social: r=0.1310
“CAMCOG/GDS 15 contribute significant to QoL”21
Analysis of group differences:
By SES, 3 levels: S10
By Webster, 3 levels: S (all, except emotional)21
PLQα Total scale: 0.9512Total scale:++12 Generic HRQoL scales: 9 Subscales, 1 or 2 factors/subscale, >50% variance122 Week interval
    r=0.8712EORTC QLQ30: r=0.67 (n=111)12No external criterion
α Subscales: 0.62–0.8712 Disease specific measures: Depression(n=16)12
Subscales:H and Y: r=0.27, NS (n=21–29)12Physical achievement
Correlation subscale–total scale:    r=0.69–0.8612SES: r=−0.27, NS (n=21–29)12Leisure
    r=0.73–0.8612    (n=65; 14 days) Other measures: Concentration
    (n=405)QoL VAS: r=−0.28, NS (n=21–29)12Social integration
ADL scale: r=0.73 (n=111)12Insecurity
Activity limitation
PIMSα Total scale: 0.9011ICC=0.721111 Analysis of group differences: 4 Factors, 72% variance11:0
(n=149; 1 month)(Consensus)By self assessed fluctuations: S (only between stable patients and fluctuating patients at their worst)11Psychological
Correlation among factors:Social