Table 1

 Data from Levyet al 1 about patients with non-traumatic coma of more than six hours duration (excluding drug induced coma), showing the relation between physical signs at 24 hours and their long term outcome

Severe disability or worse Moderate or good recovery Sensitivity Specificity Positive predictive value Negative predictive value Likelihood ratio (positive test) Likelihood ratio(negative test)
Verbal response
Incomprehensible or none187450.960.260.810.67 1.30 0.16
Orientated, confused or inappropriate816
Eye opening response
To pain/none270420.890.480.870.53 1.69 0.24
Spontaneous/to noise3438
Pupillary light reflex
Absent7810.260.990.990.26 20.59 0.75
Corneal reflex
Absent9000.321.001.000.29 201-150 0.68
Spontaneous eye movements
Roving dysconjugate, other or none210190.690.770.920.40 2.94 0.40
Orienting or roving conjugate9462
Oculocephalic responses
Abnormal/absent292610.960.240.830.59 1.26 0.18
Oculovestibular responses
Abnormal265450.960.320.850.64 1.40 0.14
Motor responses (best limb)
Flexion, extension or none206150.680.810.930.40 3.66 0.40
Obeying, localising or withdrawing9866
Deep tendon reflexes
Absent6740.240.950.940.26 4.67 0.80
Skeletal muscle tone
Absent12080.440.890.940.30 3.98 0.63
  • 1-150 Not able to calculate exactly.