Table 1

Scores on efficacy measures at baseline and after treatment with donepezil and placebo

After 6 weeksAfter 10 weeks
BaselineDonepezilPlaceboDonepezilPlacebo
Values are mean (SD) or number (%) of patients with at least one score after the baseline.
*p<0.05 compared with placebo (repeated measurements analysis of variance).
MMSE, Mini-mental state examination; UPDRS, unified Parkinson's disease rating scale; CIBIC+, Clinician's interview based impression of change based on carer information.
MMSE score20.8 (3.4)22.7 (3.6)*19.9 (4.0)22.8 (3.7)*21.0 (5.0)
CIBIC+ score3.1 (0.9)*3.7 (0.5)3.3 (0.9)*4.1 (0.8)
UPDRS motor score32.1 (15.2)31.8 (15.4)35.1 (8.1)
Subjective impression of parkinsonism3.6 (1.2)3.8 (1.4)3.7 (1.1)4.2 (1.5)