Demographic features, apolipoprotein E genotypes, total cholesterol (TC), and lipoprotein(a) (Lp(a)) in patients with Alzheimer's disease (AD)
| With AD | Without AD | |||
|---|---|---|---|---|
| Variable | Men | Women | Men | Women |
| *ε2/ε2, ε2/ε3, and ε2/ε4 genotypes; †ε3/ε4, and ε4/ε4 genotypes. Data are mean (SD) unless otherwise indicated. | ||||
| Number | 18 | 43 | 30 | 33 |
| Age (years) | 74.2 (7.8) | 70.2 (10.1) | 68.4 (10.6) | 67 (10.8) |
| Apolipoprotein E ε2 carrier* | 3 (16.7%) | 2 (4.7%) | 15 (50%) | 15 (45.5%) |
| Apolipoprotein E ε3 homozygous | 10 (55.6%) | 28 (65.1%) | 11 (36.7%) | 14 (42.4%) |
| Apolipoprotein E ε4 carrier† | 5 (27.8%) | 13 (30.2%) | 4 (13.3%) | 4 (12.1%) |
| TC (mmol/l) | 4.89 (1.13) | 5.01 (0.97) | 6.08 (0.98) | 5.19 (1.17) |
| Lp(a) (mg/l) | 149.3 (181.2) | 225.0 (255.2) | 159.4 (201.9) | 219.8 (257.7) |
| 25th, 50th, and 75th percentiles | 4.38, 8.83, 17.50 | 1.82, 9.61, 42.50 | 1.38, 5.85, 23.00 | 1.00, 7.00, 43.61 |