Change in odds ratio of having AD for Lp(a) serum concentrations controlling for age (coded 1 if ≥72 years old), TC, sex (coded 1 if female), and apolipoprotein E ε4 carrier (coded 1 if apolipoprotein E ε4 carrier)
Lp(a), controlling for age | Lp(a), controlling for age and TC | Lp(a), controlling for age and sex | Lp(a), controlling for age and apolipoprotein E ε4 carrier | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Lp(a) (mg/l) | Age (years) | With AD | Without AD | Odds ratio | 95% CI | Odds ratio | 95% CI | Odds ratio | 95% CI | Odds ratio | 95% CI |
≤14.5 | ≥72 | 4 | 6 | 2.13 | 0.40 to 11.28 | 2.10 | 0.36 to 12.26 | 2.03 | 0.41 to 10.07 | 2.41 | 0.43 to 13.46 |
<72 | 5 | 16 | |||||||||
15.0–65.0 | ≥72 | 9 | 6 | 2.14 | 0.50 to 9.25 | 1.63 | 0.44 to 6.10 | 2.34 | 0.55 to 9.94 | 2.13 | 0.48 to 9.54 |
<72 | 7 | 10 | |||||||||
70.0–355.0 | ≥72 | 17 | 2 | 19.13 | 1.73 to 211.5 | 11.33 | 1.26 to 101.9 | 24.17 | 1.66 to 350.9 | 19.50 | 1.47 to 257.9 |
<72 | 4 | 9 | |||||||||
≥360 | ≥72 | 7 | 12 | 0.15 | 0.02 to 1.10 | 0.15 | 0.01 to 1.15 | 0.14 | 0.02 to 1.27 | 0.13 | 0.02 to 1.14 |
<72 | 8 | 2 |