Number of VFDs depending on cumulative dose of vigabatrin received (daily dose × number of days treated)
| Total vigabatrin dose (kg) | Range | Number of patients tested | Number of vigabatrin VFDs (%) |
|---|---|---|---|
| χ2 = 1.359, four df (p > 0.5). VFDs, visual field defects on testing from any cause; Vigabatrin VFDs, visual field defects that the examining ophthalmologist felt likely to be due to vigabatrin. | |||
| <2 | 0.09–1.96 | 10 | 3 (30) |
| 2–4 | 2.01–3.95 | 28 | 12 (43) |
| 4–6 | 4.02–5.56 | 24 | 10 (42) |
| 6–10 | 6.03–8.52 | 21 | 9 (43) |
| >10 | 10.22–19.72 | 15 | 8 (53) |