Raw and adjusted callosal measures (mm2) in subjects with questionable and mild dementia (n=83)
| Control group (n=33) | Questionable dementia (n=27) | Mild dementia (n=23) | ||
|---|---|---|---|---|
| Values are mean (SD). | ||||
| *The duration of symptoms was calculated only in a subset of patients (14 with questionable dementia, 21 with mild dementia). The remaining subjects could not give information about symptom duration. | ||||
| CC1–CC5, corpus callosum segments; F, female; M, male; MMSE, mini-mental state examination. | ||||
| Sex | 16 M / 17 F | 7 M / 20 F | 10 M / 13 F | |
| Age (years) | 78.6 (2.8) | 78.9 (2.9) | 78.0 (3.3) | |
| MMSE | 28.9 (0.8) | 26.0 (1.8) | 22.0 (1.8) | |
| Years of education | 12.4 (2.1) | 11.0 (1.7) | 12.0 (1.9) | |
| Duration of symptoms (months)* | – | 23.7 (23.4) | 31.2 (25.6) | |
| Raw callosal measures | CC1 | 163.3 (22.4) | 156.6 (23.9) | 145.5 (24.9) |
| CC2 | 80.5 (12.6) | 76.9 (10.3) | 76.0 (12.6) | |
| CC3 | 77.9 (11.5) | 73.5 (10.3) | 71.0 (8.7) | |
| CC4 | 75.6 (13.4) | 70.5 (10.2) | 68.0 (10.2) | |
| CC5 | 171.2 (26.5) | 163.4 (33.4) | 155.6 (30.0) | |
| Total CC | 568.5 (69.8) | 540.9 (69.7) | 516.0 (69.8) | |
| Callosal measures adjusted by intracranial area | CC1 | 1.14 (0.15) | 1.11 (0.15) | 1.03 (0.18) |
| CC2 | 0.56 (0.08) | 0.55 (0.07) | 0.54 (0.10) | |
| CC3 | 0.55 (0.08) | 0.52 (0.07) | 0.50 (0.07) | |
| CC4 | 0.53 (0.09) | 0.50 (0.08) | 0.48 (0.08) | |
| CC5 | 1.20 (0.18) | 1.16 (0.21) | 1.10 (0.21) | |
| Total CC | 3.98 (0.47) | 3.83 (0.42) | 3.66 (0.53) | |