Volumes (mm3) of the hippocampal subregions for each group
SVD | p Value | AD | p Value | Control | |
---|---|---|---|---|---|
Values are mean (SEM). Values significantly different from controls are shown in bold. | |||||
SVD, Small vessel disease; AD, Alzheimer's disease. | |||||
Total | 1302 (142) | 0.0053 | 1035 (74) | 0.0001 | 1835 (108) |
CA1 | 466 (77) | 0.0270 | 317 (46) | 0.0004 | 662 (46) |
CA2–3 | 119 (10) | 0.5813 | 89 (14) | 0.0344 | 129 (12) |
CA4 | 160 (8) | 0.4187 | 158 (12) | 0.3516 | 185 (25) |
Dentate gyrus | 51 (2) | 0.6050 | 59 (5) | 0.0924 | 47 (4) |
Subiculum | 254 (37) | 0.0112 | 211 (23) | 0.0025 | 490 (66) |
Presubiculum | 251 (36) | 0.0668 | 201 (26) | 0.0028 | 322 (17) |