Table 3

Meta analysis of association studies investigating genes for PD67

GeneGene ProductSignificant association in meta analysis
OR, odds ratio of developing PD.
DRD2Dopamine receptor 2No
DRD4Dopamine receptor 4No
DATDopamine transporterNo
MAOAMonoamine oxidase ANo
MAOBMonoamine oxidase BYes (OR 2.58)
COMTCatechol-o-methyl-transferaseNo
NAT2N-acetyl transferase 2 detoxification enzymeYes (OR 1.36)
APOEApo-lipoprotein ENo
GSTT1Glutathione transferase detoxification enzyme T1Yes (OR 1.34)
GSTM1Glutathione transferase detoxification enzyme M1No
GSTP1Glutathione transferase detoxification enzyme P1No
GSTZ1Glutathione transferase detoxification enzyme Z1No
tRNA GlutRNA Glu mitochondrial geneYes (OR 3.0)
ND2Complex 1 mitochondrial geneNo