Table 2

Clinical and laboratory findings for patients with anti-GT1a IgG lacking cross reactivity with GQ1b

Patient 1Patient 2Patient 3Patient 4Patient 5
*Hughes functional grading scale.
URTI, Upper respiratory tract infection; BP, blood pressure; PP, plasmapheresis; IVIg, intravenous immunoglobulin.
Age (years)/sex60/male21/female59/male39/female21/male
Previous symptoms
    URTI
    Diarrhoea++++
    Headache
Neurological findings
    Consciousness disturbance
    Ophthalmoplegia/diplopia+
    Facial palsy+++
    Bulbar palsy+++++
    Neck weakness+++++
    Limb weaknessArm dominantOnly in armsNo dominanceNo dominanceNo dominance
    Pyramidal sign
    AtaxiaCerebellar ataxia
    Sensory disturbance
    Autonomic disfunctionArrhythmia BP change
Ganglioside antibody
    IgG (titre)GT1a (128000)GT1a (128000)GT1a (8000)GT1a (16000)GT1a (32000)
GT1b (16000)GQ1b (8000)GM1 (8000)
GD1a (4000)GD1a (2000)
GQ1b (4000)
    IgM (titre)GM1b (4000)
GalNAc-GD1a (4000)
C jejuni serology+++++
Nerve conduction study resultsNot availableNormalAxonalNot availableNot available
TreatmentPPPPNonePPPP+IVIg
Ventilation+++
Disability scale* at nadir52255