Prognostic factors using Cox's proportional hazards model
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Parameter | Hazard ratio | 95% CI | p Value | Hazard ratio | 95% CI | p Value |
| A, astrocytoma; CI, confidence interval; KPS, Karnofsky performance status; OA, oligoastrocytoma; PDGFR, platelet derived growth factor receptor. | ||||||
| KPS (≥90 v ≤80) | 0.40 | 0.18 to 0.92 | 0.03 | 0.33 | 0.14 to 0.75 | 0.009 |
| PDGFRα | 0.96 | 0.94 to 0.99 | 0.04 | 0.96 | 0.93 to 0.99 | 0.02 |
| Age (>45 years v ≤45 years) | 1.49 | 0.72 to 3.08 | 0.29 | 1.60 | 0.76 to 3.39 | 0.22 |
| Preop duration of symptoms | 1.00 | 0.99 to 1.01 | 0.38 | – | – | – |
| Side (left v right) | 1.35 | 0.67 to 2.70 | 0.40 | – | – | – |
| Contrast enhancement | 1.32 | 0.66 to 2.63 | 0.44 | – | – | – |
| Histology (A v OA) | 1.39 | 0.53 to 3.62 | 0.51 | – | – | – |
| Sex (male v female) | 1.33 | 0.57 to 3.11 | 0.51 | – | – | – |
| Epilepsy only | 0.91 | 0.45 to 1.85 | 0.79 | – | – | – |
| Total resection | 0.84 | 0.36 to 1.97 | 0.69 | – | – | – |
| Radiotherapy (yes v no) | 1.98 | 0.60 to 2.63 | 0.23 | – | – | – |