Apolipoprotein E ε4 carriers | Apolipoprotein E ε4 non-carriers | |||
---|---|---|---|---|

PIK3R1 | AD (n=86) | Controls (n=132) | AD (n=116) | Controls (n=38) |

*p<0.05). Data are number (%). | ||||

Genotypes | ||||

GG | 66 (0.77) | 85 (0.65) | 85 (0.73) | 27 (0.71) |

GA + | 20 (0.23) | 44 (0.33) | 28 (0.24) | 10 (0.26) |

AA | – | 3 (0.02) | 3 (0.03) | 1 (0.03) |

OR 1.88, CI 1.00 to 3.52, p=0.05 | OR 1.21, CI 0.53 to 2.77, p=0.65 | |||

Alleles | ||||

G | 152 (0.88) | 214 (0.81) | 198 (0.85) | 64 (0.84) |

A | 20 (0.12) | 50 (0.19) | 34 (0.15) | 12 (0.16) |

OR 1.92, CI 1.05 to 3.51, p=0.03* | OR 1.15, CI 0.56 to 2.35, p=0.70 |