Table 4

Results from voxel based morphometry: regression analyses

Analysis	Contrast	Region	Voxel cluster	SPM _{z}	Peak coordinates
Region, spatial extent (voxel cluster), significance extent (SPM_{z}), and Talairach coordinates of peak effect are indicated. All results are reported at p < 0.05 (corrected for multiple comparisons).
AE, age of onset of epilapsy; AG, angular gyrus; CG, cingulate gyrus; CS, cingulate sulcus; DE, duration of epilepsy; GMC, grey matter concentration; LSSO, left sided seizure onset; MFG, middle frontal gyrus; PoCG, postcentral gyrus; PrCG, precentral gyrus; RSSO, right sided seizure onset; SFG, superior frontal gyrus.
All patients – DE, AE	GMC reduction	Bilateral thalamus	6790	7.44	9.9	−16.4	4.5
		Bilateral SFG, CG, CS, PrCG	9234	6.56	3.0	41.8	37.5
		Right cerebellum	7521	6.51	40.7	−56.5	−37.7
		Left cerebellum	7778	6.41	−41.7	−56.2	−31.7
		Left MFG, SFG	2382	6.12	−46.7	−1.9	41.4
		Right PoCG, AG	1786	5.67	40.7	−38.5	48.7
LSSO patients – DE, AE	GMC reduction
		Right thalamus	2651	6.01	12.5	−12.1	8.5
		Left thalamus	1482	5.78	−12.9	−12.3	8.9
		Bilateral SFG	1241	5.49	2.5	46.2	38.6
		Bilateral PrCG	948	5.45	−11.9	−39.8	61.7
RSSO patients– DE, AE	GMC reduction
		Right thalamus	2487	5.98	9.9	−16.4	4.5
		Left thalamus	1528	5.76	−12.9	−12.3	8.9
		Left cerebellum	5123	5.62	−41.7	−56.2	−31.7