Effect of stimulation on essential tremor and activities of daily living
| Score (item from ETRS) | Group | Baseline | One year | Six years | ||
|---|---|---|---|---|---|---|
| Off stimulation | On stimulation | Off stimulation | On stimulation | |||
| Values are mean (SD). | ||||||
| Significance v baseline: *p<0.05, **p<0.001. | ||||||
| Significance on v OFF state: †p<0.05, ††p<0.001. ADL, activities of daily living; ETRS, essential tremor rating scale. | ||||||
| Tremor ETRS (item 1–9) | All | 17.6 (7.5) (n=19) | 15.1 (6.6) (n=18) | 8.2 (5.4) (n=19)**†† | 19.4 (9.2) (n=19) | 10.4 (5.4) (n=19)**†† |
| Voice tremor (item 3) | All | 0.5 (0.6) (n=19) | 0.3 (0.5) (n=19) | 0.2 (0.4) (n=19) | 0.8 (1.1) (n=19) | 0.4 (0.6) (n=19) |
| Unilateral | 0.4 (0.5) (n=14) | 0.1 (0.4) (n=14) | 0.1 (0.3) (n=14) | 0.6 (1.0) (n=12) | 0.3 (0.5) (n=12) | |
| Bilateral | 1.0 (0.8) (n=4) | 0.8 (0.5) (n=4) | 0.5 (0.6) (n=4) | 1.3 (1.1) (n=7) | 0.4 (0.8) (n=7) | |
| Head tremor (item 4) | All | 1.2 (1.5) (n=19) | 0.9 (1.5) (n=19) | 0.7 (1.4) (n=19) | 1.2 (2.1) (n=19) | 0.5 (1.1) (n=19)*† |
| Unilateral | 1.1 (1.4) (n=14) | 0.9 (1.7) (n=14) | 0.9 (1.7) (n=14) | 0.8 (1.8) (n=12) | 0.6 (1.2) (n=12) | |
| Bilateral | 2.0 (1.8) (n=4) | 0.8 (1.0) (n=4) | 0.3 (0.5) (n=4) | 1.9 (2.5) (n=7) | 0.3 (0.8) (n=7) | |
| ADL ETRS (items 15–21) | All | 13.7 (3.7) (n=17) | 13.6 (7.9) (n=14) | 2.4 (2.7) (n=15)**†† | 17.4 (6.8) (n=16)* | 8.4 (6.0) (n=18)**†† |
| Hand function (items 10–14) | All | 26.1 (6.4) (n=19) | 24.0 (6.9) (n=19) | 14.2 (5.6) (n=19)**†† | 25.6 (7.7) (n=17) | 16.4 (6.4) (n=17)**†† |