Patient 1 (35 years; male)
|
β Adrenergic receptor sites/cell |
2300
| 2100 | 2500 | 2269 | 2800 | 2500 |
MRI, brain | 1 new E | 1 new E | 1 new E, 1 old E | – | 1 new E | 1 old E |
MRI, spinal cord | – | – | – | – | – | – |
Clinical status | RM | RM | RM | RM | RM | RM |
Kurtzke score | 6.5 | 6.5 | 7.0 | 7.5 | 7.5 | 7.5 |
Patient 2 (35 years; female)
|
β Adrenergic receptor sites/cell |
2900
| 2800 | 2980 | 2961 | 2650 | 3000 |
MRI, brain | 5 new E | 3 new E, 4 old E | 10 new E, 3 old E | 12 new E, 4 old E | 4 new E, 10 old E | 9 new E |
MRI, spinal cord | – | – | – | – | – | – |
Clinical status | RM | RL | RL | RL | RL | RL |
Kurtzke score | 6.0 | 6.0 | 6.0 | 6.0 | 6.0 | 6.5 |
Patient 3 (38 years; female)
|
β Adrenergic receptor sites/cell |
2900
| 2400 | 2860 | 2950 | 2290 | 1900 |
MRI, brain | – | 1 new E | 1 old E | – | – | – |
MRI, spinal cord | – | 1 new E | – | 1 new E | – | – |
Clinical status | RM | RM | RM | RM | RM | RM |
Kurtzke score | 4.0 | 4.0 | 4.0 | 5.0 | 5.0 | 6.0 |
Patient 4 (46 years; male)
|
β Adrenergic receptor sites/cell | 1200 | 1300 | 1430 | 1500 | 1480 | 1300 |
MRI, brain | – | – | – | – | – | – |
MRI, spinal cord | – | – | – | – | – | – |
Clinical status | RM | RM | RM | RM | RM | RM |
Kurtzke score | 6.0 | 6.0 | 6.0 | 6.0 | 6.0 | 6.0 |
Patient 5 (36 years; female)
|
β Adrenergic receptor sites/cell |
2200
| 2500 | 2600 | 2800 | 2900 | 2800 |
MRI, brain | – | – | 1 new E | 1 old E | – | – |
MRI, spinal cord | – | – | – | – | – | – |
Clinical status | RM | RM | RM | RM | RM | RM |
Kurtzke score | 7.0 | 7.0 | 7.0 | 7.0 | 7.0 | 7.5 |