Clinical data and neurophysiological findings in seven patients with neuropathy
1 | 2 | 3 | 4 | 5 | 6 | 7 | |
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All conduction measurements were within normal limits. A, high amplitude of MUPs; D, long duration of MUPs. | |||||||
*Abnormal value. | |||||||
Disease | Coeliac disease | Coeliac disease | Coeliac disease | Coeliac disease | Coeliac disease | Coeliac disease | Reflux disease |
Time from diagnosis (y) | 3 | 2 | 3 | 4 | 2 | 3 | 6 |
Sex | male | female | female | female | female | male | male |
Age | 70 | 56 | 77 | 65 | 60 | 67 | 54 |
Possible predisposing factor | no | no | no | no | Graves’ disease | alcohol | no |
Clinical/subclinical neuropathy | clinical | clinical | subclinical | subclinical | subclinical | clinical | clinical |
Motor nerve conduction | |||||||
Median nerve (elbow–wrist) | |||||||
Amplitude (mV) | 3.4 | 2.1 | 3.3 | 8.2 | 3.9 | 3.4 | 3.7 |
Velocity (m/s) | 54 | 53 | 49 | 54 | 64 | 52 | 56 |
Ulnar nerve (elbow–wrist) | |||||||
Amplitude (mV) | 8.3 | 6.2 | 7.5 | 8.6 | 11 | 6.9 | 6.5 |
Velocity (m/s) | 55 | 66 | 63 | 64 | 66 | 49 | 64 |
Peroneal nerve (knee–ankle) | |||||||
Amplitude (mV) | 3.2 | 3.2 | 3.2 | 4.6 | 4.5 | 6.6 | 8.2 |
Velocity (m/s) | 37 | 42 | 44 | 48 | 46 | 42 | 46 |
Sensory nerve conduction | |||||||
Median nerve (wrist–digit 2) | |||||||
Amplitude (μV) | 6.1 | 45 | 4.8 | 38 | 28 | 8.5 | 24 |
Velocity (m/s) | 54 | 56 | 48 | 58 | 67 | 50 | 58 |
Ulnar nerve (wrist–digit 5) | |||||||
Amplitude (μV) | 3.5 | 21 | 5.8 | 31 | 23 | 11 | 19 |
Velocity (m/s) | 59 | 54 | 40 | 58 | 54 | 56 | 61 |
Sural nerve (calf–ankle) | |||||||
Amplitude (μV) | 2.7 | 4.4 | 7.3 | 4.7 | 8.2 | 12 | 4.4 |
Velocity (m/s) | 48 | 54 | 45 | 47 | 54 | 42 | 64 |
EMG findings | |||||||
m tibialis anterior | |||||||
mean amplitude (SD) | 4* | 1.5 | 1.2 | 1.6 | 0.2 | 1.1 | 1.3 |
duration of MUPs (SD) | 3.6* | 2.5* | 2.9* | 3.9* | 3.4* | 0 | 2 |
Number of outliers | A9*, D3* | A1, D3* | A1, D7* | A2, D3* | A0, D1 | A0, D0l | A3*, D2 |
m biceps brachii | |||||||
mean amplitude (SD) | 0.3 | 2.3 | 1.8 | 0.6 | 0 | 2.7* | 0.6 |
duration of MUPs (SD) | 0.2 | 1.8 | -0.7 | 1.2 | 1.5 | 0.1 | 0 |
Number of outliers | A0, D1 | A0, D0 | A1, D0 | A0, D1 | A0, D5* | A0, D0 | A0, D2 |
Heat pain threshold (°C) | |||||||
Left thenar | 54.4 | 47.1 | 44.7 | 50.5 | 49.4 | 48.1 | 49.2 |
Left foot | 49.4 | 48.3 | 47.3 | 47.0 | 47.5 | 46.6 | 45.3 |
Tactile threshold (as10log of force, mg compressing skin) | |||||||
Left leg | |||||||
Dermatome L3 | 3.84 | 4.74* | 5.07* | 3.84 | 4.08 | 4.17 | 2.44 |
Dermatome S1 | 3.84 | 4.56 | 4.31 | 4.08 | 4.08 | 4.08 | 4.56 |