Table 1

Age and sex specific annual incidence rates (per million) of myasthenia gravis in Estonia during the period 1970 to 1996

Age group (years)	Mean annual population 1983			Cases of myasthenia gravis			Incidence rates (95%CI)			p Values*
Age group (years)	Men	Women	Total	Men	Women	Total	Men	Women	Total	p Values*
*Statistical differences between the rates in men v women.
0–9	114 396	109 472	223 868	4	2	6	1.3 (0.3 to 3.3)	0.7 (0.1 to 2.49)	1.0 (0.4 to 2.2)	0.4472
10–19	108 410	100 849	209 259	8	16	24	2.7 (1.2 to 5.4)	5.9 (3.4 to 9.5)	4.2 (2.7 to 6.3)	0.0702
20–29	118 253	115 044	233 297	5	18	23	1.6 (0.5 to 3.6)	5.8 (3.4 to 9.2)	3.7 (2.3 to 5.5)	0.00544
30–39	102 469	105 421	207 890	6	21	27	2.2 (0.8 to 4.7)	7.4 (4.6 to 11.3)	4.8 (3.2 to 7.0)	0.00496
40–49	97 321	106 258	203 579	5	13	18	1.9 (0.6 to 4.4)	4.5 (2.4 to 7.7)	3.3 (1.9 to 5.2)	0.0892
50–59	82 189	107 251	189 440	8	17	25	3.6 (1.6 to 7.1)	5.9 (3.4 to 9.4)	4.9 (3.2 to 7.2)	0.2502
60–69	41 067	72 715	113 782	5	19	24	4.5 (1.5 to 10.5)	9.7 (5.8 to 15.1)	7.8 (5.0 to 11.6)	0.1188
70–79	2 8287	63 939	92 226	8	7	15	10.5 (4.5 to 20.6)	4.1 (1.6 to 8.4)	6.0 (3.4 to 9.9)	0.0574
80–89	7827	27 097	34 924	0	0	0	0.0 (0.0 to 14.2)	0.0 (0.0 to 4.1)	0.0 (0.0 to 3.2)
Total	700 219	808 046	1 508 265	49	113	162	2.6 (1.9 to 3.4)	5.2 (4.3 to 6.3)	4.0 (3.4 to 4.7)	<0.001
Adjusted to the European standard population							2.8 (2.0 to 3.6)	5.2 (4.3 to 6.3)	4.0 (3.4 to 4.7)	<0.001
Adjusted to the world standard population							2.5 (1.8 to 3.3)	4.9 (4.0 to 5.9)	3.7 (3.2 to 4.3)	<0.001