Table 2

CSF hypocretin-1 in patients with narcolepsy without cataplexy, idiopathic and other hypersomnias

DiagnosisCentreAgeSexAge of onsetFamily historyECHHSPMSLTSOREMPsRDIHLA DQB1*0602Hypo-1
Centre 1: Montpellier, France; Centre 2: Zurich, Switzerland
F, female; M, male; E, Epworth sleepiness scale; HH, hypnagogic hallucination; SP, sleep paralysis; RDI, respiratory disturbances index including oesophageal pressure monitoring; Hypo-1, level of hypocretin-1 in the CSF (pg/ml); na, not available
Family history: 0, none; H, family history of hypersomnia
* HLA DRB1*07/08-DQB1*02/04
Narcolepsy without cataplexy
1*118M14017723.4346
2134F8016+3.320.7+597
3126F16019++13.81<5+100
4222M20015+6.530.8+236
5231M25018++343.9+393
6250M30na16+733.1+419
7237F21H21++5.450.9+490
8239F30H17+441.2+537
9237M19016+5.531.6+591
Idiopathic hypersomnia
1131M310194.411.1+609
2236M26014501.4204
3261M210175.202+327
4228F22H16401.1342
5249F370156.401.8400
6236M300177.103.5+421
7241M350144.200.91130
Post-traumatic hypersomnia
1229M230174.502176
2240M21019303.1+503
Sleep apnoea syndrome
1149M14022+2.1427.8476
Myotonic dystrophy
1123M19H186.435401