Strategies for gene therapy in the CNS using viral vectors
| Reprinted by permission of Oxford University Press from ref 53. | |
| (1) | Replace missing or defective gene |
| (2) | Replace or enhance local growth factors or enzyme production |
| (3) | Virus directed enzyme pro-drug treatment |
| (4) | Direct cell killing of CNS tumours |
| (5) | Delivery of anti-sense sequences to particular genes |
| (6) | Use of inserted DNA to increase cellular antigen expression, to boost immune response |