Effects of treatment with D2 agonists on ratios of specific to non-specific [123I]β-CIT binding in the whole striatum
| Striatal [123I]β-CIT binding ratio | |||||
|---|---|---|---|---|---|
| Patient No | Sex | Protocol | Drug (mg/day) | On treatment | Drug-naive/withdrawn |
| F, female; M, male; protocol A, drug-naive at the time of first imaging; protocol B, approximately one year on monotherapy at the time of first imaging. | |||||
| 1 | F | B | Pergolide (1.0) | 1.72 | 1.79 |
| 2 | M | B | Pergolide (2.0) | 1.95 | 2.30 |
| 3 | M | B | Pergolide (2.0) | 1.63 | 1.66 |
| 4 | M | A | Pergolide (2.0) | 2.13 | 1.88 |
| 5 | F | A | Pramipexol (2.25) | 2.86 | 2.49 |
| 6 | M | A | Pergolide (1.5) | 1.86 | 2.10 |
| 7 | M | A | Pergolide (1.5) | 3.25 | 3.78 |
| 8 | M | A | Pergolide (2.0) | 2.22 | 2.22 |
| 9 | M | A | Pergolide (1.0) | 2.70 | 2.90 |
| Mean (SD): | 2.26 (0.6) | 2.35 (0.70) | |||