Table 3

Mean annual change in the ratio of specific to non-specific [123I]β-CIT binding in 50 patients with early stage Parkinson’s disease

Baseline ratioFollow up ratioRelative change
Values are mean (SD).
The relative change in [123I]β-CIT binding ratios within one year was calculated using the formula: [follow up SPECT imaging minus baseline SPECT imaging]/[baseline SPECT imaging] × 100%See end of article for authors’ affiliations [mean follow up SPECT imaging] − [mean baseline SPECT imaging]/[mean baseline SPECT imaging] ×100%.
*Significant relative difference between the mean values of two imaging assessments (paired samples two tailed t test; p < 0.05).
Striatum, whole2.6 (0.7)2.4 (0.7)−7.6 (17.9)*
Putamen, whole2.1 (0.6)1.9 (0.5)−8.4 (18.6)*
Caudate, whole3.9 (1.0)3.7 (1.1)−4.5 (21.3)
Striatum, ipsilateral2.9 (0.8)2.6 (0.8)−7.5 (17.6)*
Striatum, contralateral2.3 (0.6)2.1 (0.7)−7.1 (20.7)*
Putamen, ipsilateral2.4 (0.7)2.2 (0.7)−8.0 (17.9)*
Putamen, contralateral1.7 (0.5)1.6 (0.5)−7.9 (25.2)*
Caudate, ipsilateral4.2 (1.1)4.0 (1.2)−4.4 (21.2)
Caudate, contralateral3.6 (1.0)3.4 (1.1)−4.5 (22.8)