Comparison of the biomarkers results using the number of true positive, true negative, false positive, and false negative patients; using these figures the sensitivity, specificity, positive predictive value, and negative predictive value were determined
| TP | TN | FP | FN | Sens | Spec | PPV | NPV | |
|---|---|---|---|---|---|---|---|---|
| *Best overall result. | ||||||||
| FN, false negative; FP, false positive; NPV, negative predictive value; PPV, positive predictive value; sens, sensitivity; spec, specificity; TN, true negative; TP, true positive. | ||||||||
| All 14-3-3 bands | 52 | 183 | 15 | 0 | 100% | 92% | 78% | 100% |
| Only strong bands | 49 | 191 | 7 | 3 | 94% | 96% | 88% | 98% |
| Densitometric analysis | 50 | 192 | 6 | 2 | 96% | 97% | 89% | 99% |
| 14-3-3 and Aβ1-42* | 52 | 194 | 4 | 0 | 100% | 98% | 93% | 100% |
| Tau | 45 | 193 | 5 | 7 | 87% | 97% | 90% | 97% |
| Tau and Aβ1-42 | 45 | 194 | 4 | 7 | 87% | 98% | 92% | 97% |