Mild to moderate dementia | Severe dementia | |||||||
---|---|---|---|---|---|---|---|---|
PDD (n=17) | DLB (n=9) | PSP (n=20) | AD (n=11) | PDD (n=18) | DLB (n=51) | PSP (n=29) | AD (n=18) | |
Values are mean (SD). | ||||||||
The diagnostic groups were compared separately in the mild and moderate-severe dementia groups using one way analysis of variance. Scheffé’s post hoc test was used for pairwise comparisons. Sex distribution was compared using χ2 tests. | ||||||||
Different from PDD: *p < 0.05, **p < 0.001; different from DLB: †p < 0.05; ††p < 0.001. | ||||||||
AD, Alzheimer’s disease; DRS, dementia rating scale; DLB, dementia with Lewy bodies; MMSE, mini-mental state examination; PDD, Parkinson’s disease with dementia; PSP, progressive supranuclear palsy. | ||||||||
Age at testing (years) | 77.2 (5.6) | 73.2 (7.2) | 66.8 (5.7)** | 80.5 (4.0) | 79.1 (5.9) | 74.3 (5.7)* | 68.1 (6.0)**†† | 77.9 (5.1) |
Female (%) | 24 | 56 | 45 | 91* | 72 | 73 | 28*†† | 72 |
Duration of disease (years) | 15.4 (5.0) | 1.9 (2.1)** | 3.7 (2.3)** | 2.6 (1.6)** | 14.7 (5.5) | 4.0 (2.7)** | 4.8 (2.3)** | 3.1 (2.2)** |
Education (years) | 9.5 (4.1) | 12.0 (4.6) | 13.3 (4.0)* | 8.6 (2.2) | 9.4 (3.5) | 14.2 (2.9)** | 14.5 (2.8)** | 9.1 (3.8)†† |
MMSE score | 23.6 (2.6) | 23.9 (2.8) | 28.1 (2.4)**† | 22.3 (3.4) | 16.6 (4.5) | 17.7 (6.3) | 26.0 (5.0)**†† | 18.2 (3.6) |
DRS score, uncorrected | 120.6 (7.0) | 118 (10.8) | 125.7 (5.3) | 125.5 (3.8) | 87.5 (23.4) | 95 (20.7) | 108.6 (16.4)*† | 104.6 (9.4) |
DRS scores, corrected for age and education | 4.8 (1.4) | 3.9 (1.2) | 4.6 (1.3) | 7.1 (1.0)**†† | 2.1 (1.0) | 0.9 (1.0)** | 1.2 (1.0)* | 2.4 (0.8)†† |