Cardiovascular autonomic and adrenal function tests
| Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
| BP, blood pressure; HR, heart rate; ACTH, adrenocortical trophic hormone. *Denotes an abnormal response. | |||
| Adrenal function | |||
| Basal cortisol + synacthen 250 IU | 513 nmol/l | 215 nmol/l | 302 nmol/l |
| 30 min | 926 nmol/l | 456 nmol/l | 554 nmol/l |
| 60 min | 1260 nmol/l | 980 nmol/l | 890 nmol/l |
| Basal ACTH | 26.7ng/l | – | – |
| Recumbent aldosterone | 77.0ng/l | 10.9ng/l* | – |
| Recumbent renin | 20mU/l | 37.0mU/l | – |
| Postural challenge | |||
| Lying/standing BP | 108/70–89/56* | 145/95–104/67* | 148/85–162/89 |
| 30:15 ratio | 1.0* | 1.0* | – |
| HR response to respiratory stimulii | |||
| Deep breathing | 4* | 2* | 4* |
| Pressor tests | |||
| Cutaneous cold | |||
| BP | 111/53–112/69 | 122/85–120/78* | 138/84–165/88 |
| HR | 75–81 | 78–88 | 70–78 |
| Isometric exercise | |||
| BP | – | 130/85–122/75* | 137/85–136/88* |
| HR | – | 77–80 | 70–68 |
| Mental arithmetic | |||
| BP | 115/80–126/71 | 127/89–120/74* | 137/83–147/93 |
| HR | 76–80 | 77–84 | 72–70 |