CSF | Serum | |||||||
---|---|---|---|---|---|---|---|---|
Cell count (cells/μl) | ||||||||
Time after onset of rash (days) | White1 | Red | Total protein (g/l) | Glucose: CSF/plasma (mmol/l) | CSF HSV-2 DNA | Oligoclonal IgG bands unique to CSF and specific for HSV | HSV-1 IgG EIA | HSV-2 IgG EIA |
1All white cell counts were predominantly lymphocytes. | ||||||||
2 Negative for HSV-1, varicella-zoster virus, cytomegalovirus, and Epstein-Barr virus DNA. | ||||||||
3After isoelectric focusing, specificity confirmed by antigen mediated blot to HSV antigen (pooled HSV-1 and HSV-2) as previously described.16 | ||||||||
4Confirmed by immunoblot to HSV-2 antigen. | ||||||||
CSF, cerebrospinal fluid; EIA, enzyme immunoassay; HSV, herpes simplex virus. | ||||||||
6 | Neg | Neg | ||||||
11 | 220 | 30 | 2.0 | 4.8/8.1 | Pos2 | No | ||
14 | 344 | 1800 | 1.0 | 4.1/6.8 | Pos2 | No | ||
20 | 75 | 1000 | 0.25 | 4.0/7.1 | Neg2 | Yes3 | ||
27 | 38 | 150 | 0.4 | 3.3/5.2 | Neg2 | Yes3 | ||
41 | Neg | Pos4 | ||||||
69 | Neg | Pos4 |