Table 1

Some of the approaches used in the management of orthostatic hypotension

Adapted from Mathias CJ, Kimber JR. Treatment of postural hypotension. J Neurol Neurosurg Psychiatry 1998;:–9.
Non-pharmacological measures
  • To be avoided

    • –sudden head-up postural change (especially on waking)

    • –prolonged recumbency

    • –straining during micturition and defaecation

    • –high environmental temperature (including hot baths)

    • –“severe” exertion

    • –large meals (especially with refined carbohydrate)

    • –alcohol

    • –drugs with vasodepressor properties

  • To be introduced

    • –head-up tilt during sleep

    • –small frequent meals

    • –High salt intake

    • –judicious exercise (including swimming)

    • –body positions and manoeuvres

  • To be considered

    • –elastic stockings

    • –abdominal binders

    • –water ingestion

Pharmacological measures
▸Starter drugFludrocortisone
▸SympathomimeticsEphedrine, midodrine
▸Specific targetingOctreotide, desmopressin, erythropoietin