Some of the drugs used in reducing hypertension in management of autonomic dysreflexia, classified according to their major site of action on the reflex arc and target organs
| *Clonidine and reserpine have multiple effects, some of which are peripheral. | ||
| Adapted from Mathias CJ, Frankel HL. Autonomic disturbances in spinal cord lesions. In: Mathias CJ, Bannister R, eds. Autonomic failure: a textbook of clinical disorders of the autonomic nervous system, 4th ed. Oxford: Oxford University Press, 2002:494–513. | ||
| ▸Afferent | Topical lignocaine | |
| ▸Spinal cord | Clonidine* | |
| Reserpine* | ||
| Spinal anaesthetics | ||
| ▸Efferent | Sympathetic ganglia | Hexamethonium |
| Sympathetic nerve terminals | Guanethidine | |
| α Adrenoceptors | Phenoxybenzamine | |
| ▸Target organs | Blood vessels | Glyceryl trinitrate |
| Nifedipine | ||