Table 1

Patient characteristics for age, sex, disease duration, ALS functional rating scale, and disease rate. Clinical examination findings divided patients into those with predominantly upper motor neuron (umn), lower motor neuron (lmn), and mixed signs. One patient with some missing clinical data was not entered into the correlation analyses between FA, MD, and clinical markers. Median values with ranges (in parentheses) are shown at the bottom of the table

SubjectAge (y)SexDisease duration (months)ALS Functional Rating ScaleDisease rate (ALS units/month)Predominant clinical signs
Patients65male36310.25umn
51male84340.07umn
66female14300.71mixed
58male36mixed
60female15260.93mixed
71male42220.43mixed
55female22250.68mixed
42male12320.67umn
53male48320.17mixed
67female27230.63lmn
Patients56male17320.47mixed
51male11281.09mixed
63male60280.20umn
70female12310.75mixed
46male7183.14mixed
63male24270.54lmn
59male24370.13mixed
28male14231.21mixed
59male18300.56mixed
57male54310.17mixed
54male23270.57mixed
Patient group58.016M:5F23280.554 umn
(28–71)(7–84)(11–37)(0.07–1.21)15 mixed
excludes outlier2 lmn
Control group51.59M:5F
(37–71)