Demography of 38 patients with PD, PD with late dementia, and pathology consistent with DLB
Clinical diagnosis | PD | PD with late dementia |
---|---|---|
Mot-Dem, interval between onset of motor symptoms and onset of dementia; Dur-Dem, duration of dementia; L, limbic; N, neocortical. | ||
Sample size | 17 | 21 |
M/F | 11/6 | 13/8 |
Age at onset, y, mean (range) | 60.3 (36–81) | 59.8 (40–71) |
Mot-Dem, y, mean (range) | – | 12.2 (6–26) |
Dur-Dem, y, mean (range) | – | 3.4 (0–7) |
Age at death, mean (range) | 75.4 (51–91) | 75.3 (57–86) |
Disease duration, y, mean (range) | 15.1 (5–28) | 15.5 (8–27) |
Response to levodopa | 17/17 | 21/21 |
Motor fluctuations | 12/17 | 10/21 |
Rest tremor | 14/17 | 15/21 |
Hallucinations | 8/17 | 16/21 |
LB count, mean (range) | 5.9 (3–10) | 7.6 (3–10) |
Neuropathological category of DLB | 9 L / 8 N | 7 L / 14 N |