Measures of parkinsonism on LD/CD, and 15 and 30 g of mucuna
| LD/CD (SD) | 15 g mucuna (SD) | 30 g mucuna (SD) | Difference LD/CD v 15 g mucuna (p value) | Difference LD/CD v 30 g mucuna (p value) | |
|---|---|---|---|---|---|
| LD/CD, l-dopa/carbidopa; SD, standard deviation. | |||||
| All times indicated in minutes. Tapping: see Methods. UPDRS refers to motor score. Partial “on”: any clinical state where parkinsonism was above baseline level before and after reaching a full “on” state. | |||||
| UPDRS baseline | 49.8 (12.7) | 49.5 (15.3) | 46.9 (10.7) | NS | 0.046 |
| Tapping baseline | 47.4 (11.0) | 44.0 (12.6) | 45.0 (13.6) | NS | NS |
| Best UPDRS “on” | 15.4 (7.8) | 15.5 (7.6) | 15.5 (8.5) | NS | NS |
| Best tapping “on” | 75.5 (21.3) | 78.5 (21.3) | 79.1 (15.0) | NS | NS |
| Duration of full “on” | 167.4 (55.3) | 147.3 (30.5) | 204.0 (55.1) | NS | 0.021 |
| Duration of full plus partial “on” | 232.0 (84.8) | 170.3 (38.0) | 278.1 (53.9) | 0.036 | 0.036 |
| Time to full “on” | 68.5 (29.0) | 45.6 (30.4) | 34.6 (13.6) | 0.035 | 0.021 |
| Time to beginning of “on” | 54.6 (24.5) | 27.8 (14.1) | 23.0 (11.5) | 0.012 | 0.012 |