Table 1

Between group analysis (two sample t test, SPM99): regions of relative accelerated loss of grey matter volume in patients v controls (modulated data)

Talairach coordinates			Region
x	y	z	Hemisphere	Anatomic	Brodman area	Z statistic
BA, Brodman area; L, left; R, right; Z, maximum ζ value (voxel level uncorrected p<0.001, cluster level corrected p<0.05).
−27	−60	63	L	Superior parietal lobule	BA 7	5.54
−43	2	38	L	Middle frontal gyrus	BA 9	5.38
−31	−65	58	L	Superior parietal lobule	BA 7	5.20
−65	−52	8	R	Middle temporal gyrus	BA 39	5.13
19	−15	72	R	Superior frontal gyrus	BA 6	5.10
47	−76	25	L	Superior temporal gyrus	BA 22	5.10
31	−61	60	R	Superior parietal lobule/precuneus	BA 7	5.05
27	−9	52	R	Precentral gyrus	BA 4	4.94
−67	−10	26	L	Postcentral gyrus	BA 1–3	4.89
−2	14	8	L	Caudate	–	4.88
49	−12	28	R	Precentral gyrus	BA 4	4.87
3	5	69	R	Superior frontal gyrus	BA 6	4.81
−47	23	35	L	Middle frontal gyrus	BA 9	4.78
−69	−37	20	L	Middle temporal gyrus	BA 21	4.77
19	−79	48	R	Superior parietal lobule/precuneus	BA 7	4.76
27	−81	35	R	Superior parietal lobule/precuneus	BA 7	4.65
49	2	31	R	Inferior frontal gyrus	BA 4	4.63
−33	−66	36	L	Superior occipital gyrus	BA 19	4.61
55	−6	22	R	Precentral gyrus	BA 4	4.60
−33	−59	43	L	Inferior parietal lobule	BA 40	4.56
−33	−69	45	R	Superior parietal lobule	BA 7	4.48