Table 1

Allele and genotype distribution of the rs387071 NOTCH4 polymorphism in the British population

rs387071nAllele distribution (%)Genotype distribution (%)
GAGGGAAA
Scotland, UK
Alzheimer’s disease cases140234 (0.84)46 (0.16)97 (0.69)40 (0.29)3 (0.02)
Control293477 (0.81)109 (0.19)194 (0.66)89 (0.30)10 (0.04)
Manchester, UK
Alzheimer’s disease cases115191 (0.83)39 (0.17)79 (0.69)33 (0.28)3 (0.03)
Control112183 (0.82)41 (0.18)75 (0.67)33 (0.29)4 (0.04)
Total
Alzheimer’s disease cases255425 (0.83)85 (0.17)176 (0.69)73 (0.29)6 (0.02)
Control405660 (0.81)150 (0.19)269 (0.66)122 (0.30)14 (0.04)