Allele and genotype distribution of the rs367398 NOTCH4 polymorphism in the British population
| rs367398 | n | Allele distribution (%) | Genotype distribution (%) | |||
|---|---|---|---|---|---|---|
| C | T | CC | CT | TT | ||
| Scotland, UK | ||||||
| Alzheimer’s disease cases | 140 | 200 (0.71) | 88 (0.29) | 70 (0.50) | 60 (0.43) | 10 (0.07) |
| Control | 293 | 381 (0.64) | 205 (0.36) | 123 (0.42) | 135 (0.46) | 35 (0.12) |
| Manchester, UK | ||||||
| Alzheimer’s disease cases | 115 | 164 (0.71) | 66 (0.29) | 58 (0.50) | 48 (0.42) | 9 (0.08) |
| Control | 112 | 151 (0.67) | 73 (0.33) | 51 (0.45) | 49 (0.44) | 12 (0.11) |
| Total | ||||||
| Alzheimer’s disease cases | 255 | 364 (0.71) | 154 (0.29) | 128 (0.50) | 108 (0.42) | 19 (0.08) |
| Control | 405 | 532 (0.66) | 278 (0.34) | 174 (0.43) | 184 (0.45) | 47 (0.12) |