Table 2

Grey matter and white matter atrophy in progressive supranuclear palsy compared with normal controls

Location	BA	Peak coordinates (mm)			Peak z score
Location	BA	x	y	z	Peak z score
Anatomical location, Brodman area (BA), Talairach’s coordinates (x, y, z), and z values of clusters with reduced volume (p<0.05 corrected for multiple comparison).
Grey matter
Medial frontal gyrus
Left	10	−3	50	−5	5.5
Right	10	5	51	−7	5.4
Left	10	−3	38	31	4.7
Right	10	4	28	35	4.7
Middle frontal gyrus
Left	9	−50	36	11	4.0
Supplementary motor area
Left	6	−6	−28	66	4.9
Right	6	8	−25	53	5.0
Insular cortex
Left		−35	10	5	4.9
Right		44	1	0	5.9
Frontal operculum
Left		−38	21	5	4.6
Right		38	22	5	4.6
Temporo-occipital region
	19/39	−65	−50	11
White matter
Frontotemporal
Left		−41	11	12	5.7
Right		37	13	13	5.2
Mesencephalon
Left cerebral peduncle		−8	−12	−15	3.9
Right cerebral peduncle		8	−11	−15	4.4
Central		2	−18	−8	4.2