Values of the mean diffusivity (<D>) and fractional anisotropy (FA) for peritumoural oedematous brain and apparently normal contralateral white matter (centrum semiovale) pre- and post-steroid treatment for the 15 patients imaged in this study
| Age/sex | Mean diffusivity, <D> (×10−6 mm2/s) | Fractional anisotropy | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Oedematous brain | Contralateral white matter | Oedematous brain | Contralateral white matter | ||||||
| Pre-steroids | Post-steroids | Pre-steroids | Post-steroids | Pre-steroids | Post-steroids | Pre-steroids | Post-steroids | ||
| *Metastasis of malignant melanoma. †Metastasis of lung carcinoma. ‡Metastasis of renal carcinoma. All values are reported as mean (SD). Bold type indicates a statistically significant change in a parameter following steroid treatment. | |||||||||
| Glioblastoma | |||||||||
| 1/55/F | 1674 (253) | 1561 (318) | 750 (18) | 740 (24) | 0.15 (0.06) | 0.16 (0.07) | 0.47 (0.10) | 0.47 (0.10) | |
| 2/50/M | 1575 (215) | 1430 (256) | 758 (24) | 766 (22) | 0.15 (0.05) | 0.17 (0.07) | 0.49 (0.05) | 0.48 (0.04) | |
| 3/61/F | 1139 (152) | 1046 (144) | 719 (25) | 716 (22) | 0.21 (0.08) | 0.21 (0.09) | 0.43 (0.05) | 0.42 (0.04) | |
| 4/65/M | 1494 (211) | 1377 (228) | 717 (46) | 711 (54) | 0.14 (0.05) | 0.15 (0.06) | 0.45 (0.13) | 0.46 (0.14) | |
| 5/71/M | 1477 (280) | 1347 (289) | 775 (63) | 733 (24) | 0.18 (0.09) | 0.19 (0.10) | 0.52 (0.07) | 0.50 (0.10) | |
| 6/42/M | 1140 (336) | 1068 (288) | 690 (25) | 704 (22) | 0.22 (0.10) | 0.20 (0.09) | 0.42 (0.08) | 0.41 (0.07) | |
| 7/75/M | 1288 (189) | 1206 (189) | 775 (75) | 767 (61) | 0.20 (0.07) | 0.19 (0.07) | 0.42 (0.13) | 0.41 (0.10) | |
| Mean | 1398 (212) | 1291 (191) | 741 (33) | 734 (26) | 0.18 (0.03) | 0.18 (0.02) | 0.46 (0.04) | 0.45 (0.04) | |
| <ε>, %; p | −7.63 (1.17); <0.01 | −0.85 (2.35); 0.36 | 3.12 (8.48); 0.55 | −1.50 (2.11); 0.11 | |||||
| Metastases | |||||||||
| 8/54/F* | 1356 (231) | 1264 (216) | 676 (24) | 696 (31) | 0.18 (0.07) | 0.19 (0.08) | 0.41 (0.09) | 0.44 (0.09) | |
| 9/59/F† | 1554 (244) | 1460 (224) | 721 (52) | 733 (55) | 0.14 (0.06) | 0.13 (0.06) | 0.42 (0.12) | 0.39 (0.12) | |
| 10/61/M‡ | 1560 (268) | 1470 (274) | 734 (42) | 728 (33) | 0.13 (0.06) | 0.13 (0.07) | 0.48 (0.10) | 0.49 (0.08) | |
| 11/53/F* | 1556 (236) | 1489 (216) | 764 (22) | 724 (24) | 0.15 (0.07) | 0.14 (0.07) | 0.49 (0.07) | 0.48 (0.11) | |
| Mean | 1507 (100) | 1421 (105) | 724 (37) | 720 (17) | 0.15 (0.02) | 0.15 (0.03) | 0.45 (0.04) | 0.45 (0.05) | |
| <ε>, %; p | −5.73 (1.04); <0.01 | −0.36 (3.60); 0.81 | −2.36 (4.13); 0.37 | −0.20 (5.36); 0.94 | |||||
| Meningioma | |||||||||
| 12/60/F | 1442 (224) | 1371 (219) | 742 (14) | 732 (12) | 0.16 (0.06) | 0.16 (0.07) | 0.46 (0.06) | 0.45 (0.07) | |
| 13/52/F | 1215 (183) | 1155 (166) | 720 (14) | 723 (20) | 0.24 (0.08) | 0.23 (0.07) | 0.44 (0.08) | 0.44 (0.08) | |
| 14/74/M | 1077 (140) | 1011 (141) | 741 (45) | 778 (43) | 0.31 (0.10) | 0.28 (0.10) | 0.45 (0.09) | 0.44 (0.08) | |
| 15/47/F | 1539 (249) | 1444 (241) | 723 (37) | 722 (35) | 0.13 (0.06) | 0.14 (0.06) | 0.38 (0.13) | 0.38 (0.12) | |
| Mean | 1318 (210) | 1245 (199) | 732 (12) | 739 (27) | 0.21 (0.08) | 0.20 (0.07) | 0.43 (0.04) | 0.43 (0.04) | |
| <ε>, %; p | −5.54 (0.70); <0.01 | 0.98 (2.77); 0.53 | −2.90 (5.09); 0.34 | −0.49 (2.12); 0.63 | |||||