Demographic and cognitive characteristics of the study population
| PS1 mutation present (n = 17) | PS1 mutation absent (n = 16) | p Value | |
|---|---|---|---|
| Values are mean (SD) or n (%). | |||
| BDI, Beck depression inventory; MMSE, mini-mental state examination; PS1, presenilin-1; WAIS, Wechsler adult intelligence scale. | |||
| Age (years) | 30.8 (1.87) | 29.1 (2.04) | 0.558 |
| Education (years) | 11.6 (0.65) | 12.5 (0.81) | 0.418 |
| Number with subjective memory complaints | 9 (53%) | 9 (56%) | 0.583 |
| BDI score | 14.4 (3.10) | 6.5 (1.66) | 0.017* |
| Number with BDI score ⩾13 | 6 (35%) | 4 (25%) | 0.397 |
| Number having sought help from a psychiatric professional | 4 (24%) | 2 (12.5%) | 0.616 |
| MMSE score | 28.0 (0.31) | 29.4 (0.18) | 0.001 |
| Trails making test–part B, time (s) | 125.3 (13.33) | 72.8 (5.28) | 0.001 |
| Wechsler memory scale, associative learning subtest–immediate recall | 16.0 (0.75) | 18.2 (0.53) | 0.027 |
| WAIS block design | 31.7 (1.79) | 36.7 (1.55) | 0.044 |