Table 1

Summary of clinical data for cases one to nine

CaseAgeSexClinical featuresDuration (days)Anti-GQ1b titreSFEMG jitter (μs)MRI featuresFollow upFinal diagnosis
AO, Acute ophthalmoparesis; F, female; M, male; MRI, magnetic resonance imaging; R, right; L, left; SFEMG, single fibre electromyography.
149MReduced eye movements, hyporeflexia, ataxia, dysarthria128080 (initial) 1706 (repeat)45.2 (initial) 22.6 (repeat)UnremarkableComplete recoveryMFS
245MR III palsy, pupil spared21828 (initial) 17 (repeat)68.5 (initial) 21.5 (repeat)R III nerve enhancementComplete recoveryAO
361MReduced eye movements72352039.7 (initial) 21.6 (repeat)Ischaemic changesComplete recoveryAO
454MReduced eye movements, ataxia143014434.5 (initial) 18.4 (repeat)UnremarkableComplete recoveryAO
552FR III palsy, pupil spared, diabetic76617.7 (mean)UnremarkableComplete recoveryDiabetic III palsy
621FR III palsy, pupil spared750.522.9 (mean)UnremarkableComplete recoveryIdiopathic III palsy
740ML III palsy, pupil spared, bilateral ptosis76284.3 (mean)UnremarkableImproved with pyridostigmineOcular myasthenia
845FReduced eye movements in all directions105857.1 (mean)UnremarkableImproved with pyridostigmineOcular myasthenia
956MR III palsy, ptosis, pupil spared1425.522.6 (mean)Thickened R cavernous sinus and dura along floor of middle cranial fossaImproved with oral prednisolone 20 mg for 2 weeksTolosa-Hunt syndrome