Table 3

Multivariate models for full scale IQ and Wisconsin card sorting test

UnivariateMultivariate
Rp Valueβp Value
NAWM, normal appearing white matter; WAIS-R, Wechsler adult intelligence scale–revised.
(A) Multivariate model for full scale IQ (WAIS-R) (R2 = 0.52)
Age 0.438 0.011*
Sex0.2030.236
Parenchymal volume0.470.009**0.2790.121
T1 lesion load0.150.4280.3910.081
T2 lesion load0.010.977−0.1280.542
Diffusivity of NAWM−0.460.009** −0.504 0.008**
(B) Multivariate model for Wisconsin card sorting test–total errors (R2 = 0.39)
Age0.2220.226
Sex−0.1560.414
Parenchymal volume−0.380.043*−0.2330.244
T1 lesion load−0.030.8910.0080.974
T2 lesion load0.080.647−0.2200.353
Diffusivity of NAWM0.410.020* 0.413 0.046*